Publications by authors named "A Papatheodorou"
Objective: To investigate whether idiopathic nonobstructive azoospermia (iNOA) has its own transcriptomic signature.
Design: Testicular tissue biopsies were retrieved, processed, and prepared for ribonucleic acid (RNA) extraction from 26 consented patients diagnosed with iNOA. Samples were grouped into four pools based on the presence of testicular spermatozoa: two replicate pools for "No presence" (Null-spz-1 and Null-spz-2 pools), one for "High presence" (High-spz pool), and one for "Rare presence" (Rare-spz pool).
A pilot study was performed using two different DNA technology platforms conducted by two laboratories to analyze DNA extracted from 83-year-old, human male skeletal remains from 16 individuals, of which there are no other viable means to identify these war victims. The workflow of the more recent developed ForenSeq Kintelligence Kit and next generation sequencing was compared to that of the standard capillary electrophoresis - short tandem repeat (STR) method (Power Plex ESX17 and Y23 Systems). The findings indicate that greater amount of useful genetic data can be gained with the Kintelligence system across the range of samples under study and particularly for samples in which partial or no STR profiles are obtained.
View Article and Find Full Text PDFObjective: To compare the morphokinetic patterns of human embryos originating from vitrified oocytes (VITRI group) with those derived from freshly collected oocytes (CONTROL group) in oocyte donation cycles.
Design: This is a retrospective observational study.
Setting: Embryolab Fertility Clinic, Embryology Lab, Thessaloniki, Greece.
Objective: To evaluate the impact of double embryo vitrification on clinical outcomes.
Methods: This retrospective cohort study included data from January 2013 to March 2021. The study group included women aged 33.