Fibrinogen, bFGF and VEGF levels during antibiotic therapy in gynecologic cancer: a preliminary report.

The role of angiogenesis in the development of neoplasia has been identified and characterized. However, antiangiogenic therapeutic intervention still requires more evidence to become recognized and successful. The aim of this study was to evaluate levels of selected proangiogenic factors, such as fibrinogen, vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in serum of patients with the gynecologic cancer on the first, third and sixth day of antibiotic therapy, routinely administered as a perioperative treatment.

Influence of antibiotic therapy on the level of selected angiogenic factors in patients with benign gynecologic tumors--preliminary report.

An increased fibrin level enhances the activity of proangiogenic factors and may contribute to tumor formation. Formation of new blood vessels during angiogenesis leads to neoplasm development through interaction with factors such as basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF) and interleukins. The aim of this study was to investigate the influence of perioperative antibiotic therapy in women with benign gynecological tumors with regard to basic fibroblast growth factor level, fibrinogen concentration and fibrin viscosity.

[Transvaginal hydrolaparoscopy].

The paper presents a simple and cheap method of transvaginal hydro-laparoscopy used for the observation women pelvic organs. The method may be useful to diagnose sterility, indefinite pains the pelvis or to control the patients previously undergoing operations. Hydro-laparoscopy was carried out in 12 patients by means of a modified 3 mm hysteroscope equipped with modified Verres needle.

[The implantation of bipolar coagulation to remove endometriosis foci].

The paper compares the results of bipolar coagulation bey means of ERBE ICC 300 diatermy coagulator and WISAP endocoagulator. The results of both types of coagulation were assessed with reference to the changes occurring on peritoneum ligamenti sacro-uterini, Douglas pouch and ovary. The best results of endometriosis foci coagulation were obtained with bipolar ball at 20-30 W; no side effects or feelings of malaise were observed in patients just after the operation or over a longer period of convalescence.

[Rapidly growing endometrial cyst of the uterus in a young woman].

A case of a rapidly growing endometriotic cyst of uterus in young women diagnosed for sterility, and previously treated by GnRH analogues was presented. The case was difficult to diagnose before the operation.