Publications by authors named "A Pakalnis"

There are limited well-studied treatments for migraine in the pediatric population. Calcitonin gene-related peptide (CGRP) inhibitors are an established safe and effective treatment in adults, and use may be appropriate for pediatric patients in certain clinical situations. We describe migraine pathophysiology as it relates to CGRP, provide an overview of available medications, and discuss clinical usage in this population.

View Article and Find Full Text PDF

Objective: We evaluated the frequency of six commonly reported adult migraine premonitory symptoms in children and adolescents with episodic and chronic migraine and elicited psychological or behavioral comorbidities that may be associated with these symptoms.

Background: Premonitory symptoms are commonly reported in the adult migraine population; however, little information is available for the pediatric population.

Methods: Data were collected on new patients being evaluated in our multidisciplinary pediatric headache clinic over a six-month time interval.

View Article and Find Full Text PDF

Headaches in children are not uncommon and have various causes. Proper neuroimaging of these children is very specific to the headache type. Care must be taken to choose and perform the most appropriate initial imaging examination in order to maximize the ability to properly determine the cause with minimum risk to the child.

View Article and Find Full Text PDF

Migraine is one of the most common neurologic conditions in pediatrics. It can be a significant stressor, causing absences from school and interruption of parents' work and family schedules. The mainstay of treatment remains educating patients about healthy lifestyle practices and the influences of sleep, stressors, and hydration on triggering migraine attacks.

View Article and Find Full Text PDF

Objective: To ascertain whether seasonal variation occurs in emergency department (ED) visits for headache among children and adolescents.

Methods: A retrospective review was conducted using the electronic medical records of ED visits for headache at a tertiary children's hospital through calendar years 2010-2014. Using ICD-9 diagnostic codes for headache and migraine, the numbers of headache visits were determined and compared by season and during school months vs summer months.

View Article and Find Full Text PDF