Publications by authors named "A Pajares"

Objective: To assess the perioperative management of haemostasis and transfusion practices in adult patients undergoing craniotomies.

Method: Online questionnaire addressed to Spanish anaesthesiologists and promoted by the Neurosciences and Haemostasis, Transfusion Medicine and Fluid Therapy Sections of SEDAR. The questionnaire was sent by email and social media, and was active between June and October 2022.

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The evolution of blood saving programs to Patient Blood Management (PBM) represents a broader and more comprehensive approach to optimize the use of the patient's own blood, thus improving clinical outcomes and minimizing the risks associated with allogeneic blood transfusion with a holistic view of socio-economic sustainability. Implementing the strategies of the three PBM pillars in any hospital center involves a transversal change throughout the organization in which it can be very useful to apply the strategy defined by Kotter at the business level for change management. The support of renowned institutions such as the World Health Organization and the European Commission demonstrates the importance and urgency of implementing PBM programs, setting guidelines at an international level and supporting the adoption of effective strategies in the management of blood transfusion at a national and institutional level.

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Introduction: Woven bone, a heterogeneous and temporary tissue in bone regeneration, is remodeled by osteoblastic and osteoclastic activity and shaped by mechanical stress to restore healthy tissue properties. Characterizing this tissue at different length scales is crucial for developing micromechanical models that optimize mechanical parameters, thereby controlling regeneration and preventing non-unions.

Methods: This study examines the temporal evolution of the mechanical properties of bone distraction callus using nanoindentation, ash analysis, micro-CT for trabecular microarchitecture, and Raman spectroscopy for mineral quality.

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Commercial PEMFC-based micro-CHP systems are operated by rule-based energy management strategies. Each of these strategies constitutes a different way to meet the household energy demand (following the heat demand, following the electricity demand, the maximum of the two, etc.).

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Article Synopsis
  • Hepatitis B core antibody (anti-HBc) screening is used in blood establishments worldwide to help prevent the transmission of hepatitis B virus (HBV), especially from donors with occult HBV infection (OBI).
  • A survey conducted revealed varied practices in HBV screening across 30 responses from 25 countries, with some establishments screening all donations for anti-HBc and HBV DNA, while others had different approaches, leading to inconsistencies in donor deferral strategies.
  • The findings highlight the need for improved confirmation of anti-HBc results to minimize unnecessary donor deferrals while balancing the risk of transmission from anti-HBc negative OBI donors, particularly in high-endemic regions where sensitive HBV DNA testing is crucial.
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