Transcriptional control of the expression of lipoprotein lipase gene by growth hormone in preadipocyte Ob1771 cells.

A direct and modulating effect of growth hormone (GH) on the regulation of the lipoprotein lipase (LPL) gene has been shown in preadipocyte Ob1771 cells. Growth hormone acts as a modulator within the physiological range of concentrations and regulates the abundance of the two species of LPL mRNAs (3.3 and 3.