Publications by authors named "A PAOLINI"
Strain Elastography Evaluation of Patellar Tendons in Dogs after TPLO/TTA for Cranial Cruciate Ligament Rupture, Qualitative and Semiquantitative Evaluation Compared with Healthy Subjects.
Animals (Basel)
October 2024
Strain elastography (SE) evaluates tissue stiffness, providing qualitative and semiquantitative evaluation, with a strain ratio (SR) > 1 indicating that the target lesion is stiffer than the reference tissue. The patellar tendon has been described as soft in healthy dogs and hard in dogs with cranial cruciate ligament rupture, but SR usefulness has not been assessed. Dogs were divided into healthy (G1) and at least 1 month after surgery (G2) groups.
View Article and Find Full Text PDFSubcutaneous lesions in dogs are common in clinical practice. This prospective clinical study aims to compare B-flow and CEUS for the characterization of subcutaneous lesions evaluating their usefulness to distinguish benign subcutaneous lesions from malignant ones. Dogs were enrolled and ultrasound cine-loops were achieved in B-mode, Colour Doppler, Power Doppler, B-flow and CEUS.
View Article and Find Full Text PDFCerebral cavernous malformations (CCMs) are anomalies of the cerebral vasculature. Loss of the CCM proteins CCM1/KRIT1, CCM2, or CCM3/PDCD10 trigger a MAPK-Krüppel-like factor 2 (KLF2) signaling cascade, which induces a pathophysiological pattern of gene expression. The downstream target genes that are activated by KLF2 are mostly unknown.
View Article and Find Full Text PDFArticle Synopsis
- Researchers are exploring extracellular vesicle (EV)-carried miRNAs as potential biomarkers for assessing tumor aggressiveness and tailoring therapies, due to their stability and tissue specificity.
- A study identified nine miRNAs significantly upregulated in RMS patients, with miR-335-5p showing promise as a marker for distinguishing ARMS from ERMS, correlating with disease severity and patient survival outcomes.
Article Synopsis
- The study aimed to evaluate the effectiveness of two different approaches for administering quadratus lumborum block (QLB) in dogs undergoing laparoscopic ovariectomy, focusing on pain control during surgery.
- A total of 15 female dogs were randomly assigned to either a lateral or latero-ventral approach for the QLB, with pain management strategies monitored throughout the procedure.
- Results indicated that the lateral approach significantly reduced the need for additional pain relief during surgery compared to the latero-ventral approach, while all dogs had similar postoperative pain scores.