[To the history of the Research and Testing Laboratory of Psychophysiological Support of Flight Operations].

The brief history of the first research and testing laboratory (psychophysiological support of flight activity) of the Scientific Research Testing Center (aerospace medicine and military ergonomics) celebrating its 55th anniversary is presented. The laboratory, which is now located in Lipetsk allows specialists of the Research and Testing Center carrying out a wide range of studies on its basis on ergonomic provision of combat effectiveness and flight safety of flight crews, studying the influence of flight work on the pilot's organism and its performance in normal and extreme conditions in close interaction in Highly skilled employees of other institutions of the Ministry of Defense. Tebre.

[STAT1: a many-sided transcription factor].

Cell homeostasis is regulated by numerous signaling proteins. Their main task is to process extracellular signals and activate the intracellular cascades of reactions that lead to the modulation of gene activity. One of the important signaling systems is the STAT family, which is comprised of seven members.

[Identification and expression of haponin, a new protein from HL-60 cells].

We found a new protein haponin (an HLDF-alike protein) in promyelocyte HL-60 cells that is immunoreactive to polyclonal antibodies against HLDFbeta. Determination of the partial primary structure of the protein allowed us to reveal an immunogenic peptide of haponin and, on the basis of the amino acid sequence of this peptide, the degenerate primers were synthesized, which enabled us to clone the full-size cDNA of haponin. The stable heterologous expression of this cDNA in E.

[The dynamic circulatory reaction of pilots to the standard test].

The examination of cardiovascular system in pilots in the process of their training has shown that the Valsalva test can execute the function of a slight or strong irritant with further changes in hemodynamics, particularly in the frequency of systoles and arterial pressure. These changes are accompanied by the shifts of cardiac volume per minute from hypo to hyper reaction. A correlation was disclosed between the reaction in the frequency of systoles and cardiac volume per minute which can be studied from the point of view of adaptation of blood circulation system to the factors of physical loads.