Coronary artery disease (CAD) and peripheral artery disease (PAD) are common and dangerous conditions that are both driven by atherosclerosis. Despite sharing many major risk factors, their disease pathophysiology is not fully understood. In this study, we aimed to better distinguish common vs.
View Article and Find Full Text PDFJ Paediatr Child Health
January 2025
Aim: SARS-CoV-2 is highly transmissible, having infected ~16 million children in the United States. Symptom severity is higher in infants compared to older children, possibly due to their ineligibility for vaccination. Concerns persist that mothers transmit infectious viral loads of SARS-CoV-2 through breast milk.
View Article and Find Full Text PDFAchieving bone union remains a significant clinical dilemma. The use of osteoinductive agents, specifically bone morphogenetic proteins (BMPs), has gained wide attention. However, multiple side effects, including increased incidence of cancer, have renewed interest in investigating alternatives that provide safer, yet effective bone regeneration.
View Article and Find Full Text PDFBackground: Superior semicircular canal dehiscence (SSCD) is a vestibular-cochlear disorder in humans in which a pathological third mobile window of the otic capsule creates changes to the flow of sound pressure energy through the perilymph/endolymph. The primary symptoms include sound-induced dizziness/vertigo, inner ear conductive hearing loss, autophony, headaches, and visual problems. We have developed an animal model of this human condition in the Mongolian Gerbil that uses surgically created SSCD to induce the condition.
View Article and Find Full Text PDF