Does recombinant human bone morphogenetic protein-2 use in adult spinal deformity increase complications and are complications associated with location of rhBMP-2 use? A prospective, multicenter study of 279 consecutive patients.

Study Design: Multicenter, prospective analysis of consecutive patients with adult spinal deformity (ASD).

Objective: Evaluate complications associated with recombinant human bone morphogenetic protein-2 (rhBMP-2) use in ASD.

Summary Of Background Data: Off-label rhBMP-2 use is common; however, underreporting of rhBMP-2 associated complications has been recently scrutinized.

Does vertebral level of pedicle subtraction osteotomy correlate with degree of spinopelvic parameter correction?

Object: Pedicle subtraction osteotomy (PSO) is a spinal realignment technique that may be used to correct sagittal spinal imbalance. Theoretically, the level and degree of resection via a PSO should impact the degree of sagittal plane correction in the setting of deformity. However, the quantitative effect of PSO level and focal angular change on postoperative spinopelvic parameters has not been well described.

Spine care: evaluation of the efficacy and cost of emerging technology.

Over the last decade a number of new technologies have been introduced to the area of spine care. Although this recent explosion of innovation has brought advances to patient care, it has also brought concerns regarding overuse, increasing costs, and safety. A value-based approach to assessing and purchasing new technology depends on a shift toward comparative effectiveness analysis, transparency in pricing and potential conflicts of interest, and an alignment of incentives and goals among purchasers, consumers, and payers.

Pain and disability determine treatment modality for older patients with adult scoliosis, while deformity guides treatment for younger patients.

Study Design: Multi-center, retrospective review.

Objective: Identify age associated clinical and radiographic features correlating with AS treatment.

Summary Of Background Data: Little information exists about factors determining treatment for adult scoliosis (AS).