[The significance of interleukin-6 and polymorphism of its gene (C174G) under viral, alcoholic and mixed cirrhosis of liver].

The study was carried out to evaluate significance of interleukin-6 (IL-6) and polymorphism of gene IL-6 (C174G) under liver cirrhosis of viral, alcoholic and mixed etiology. The blood of patients with liver cirrhosis of viral (n=48), alcoholic (n=11) and mixed (n=10) genesis was used for analyzing indices, level of IL-6 and polymorphism of gene IL-6 (C174G). In patients with liver cirrhosis independently of etiology increasing of concentration of IL-6 was established as compared with control group (p<0.

[The laboratory evaluation of dynamics of progression of liver fibrosis under chronic hepatitis].

The study was carried out to evaluate velocity of development of fibrosis of liver in patients with chronic hepatitis C using laboratory tests. The sampling of 150 patients with chronic hepatitis C were examined to analyze blood serum in phase of reactivation detecting concentration of hyaluronic acid, alpha-fetoprotein, iron, ferritin, vascular endothelial risk factor, malonic dialdehyde and activity of catalase. The degree of fibrosis of liver was evaluated using technique of ultrasound elastography.

[The oleic triglycerides of palm oil and palmitic triglycerides of creamy fat. The reaction of palmitoylation, potassium and magnesium palmitate, absorption of fatty acids by enterocytes and microbiota of large intestine].

The decreasing of content of animal, palmitic milk fat (butter) by means of its substitution with vegetable, oleic, palmy oil in food of adults optimal by its quantity is physically chemically and biologically substantiated. In oleic palmy oil higher content of oleic mono unsaturated fatty acid and oleic triglycerides than in creamy fat is established. The biologic availability of palmitic unsaturated palmitic acid in the form of free fatty acid is decreased at its absorption by enterocytes of small intestines is detected.

[FOUNDER PERM PROVINCIAL MEDICINE--"PEOPLE'S DOCTOR" F. H. GRAIL].

The article presents the biography of one wonderful doctors, who have high human, civil and professional qualities, Fyodor Ch. Gral.

[The dysfunction of endothelium and humoral mediators of blood plasma in patients with ulcerous colitis.].

The study was carried out to evaluate biological reaction of endothelium-depended vasodilation and disorder of its regulation by humoral mediators of inflammation in patients with ulcerous colitis. And also to compare disorders of function of endothelium with content of cytokines in blood plasma and severity of inflammation in intestine. The examined sampling consisted of 90 patients with diagnosis of ulcerous colitis at the phase of exacerbation of disease.