Publications by authors named "A P Ribas"

The formalin-ethyl acetate concentration technique (FECT) is one of the most sensitive diagnostic method not only for all helminths, but also for infections in stool examinations. However, it remains a diagnostic problem for light infections. We modified the one-step FECT to determine the low-intensity of infection and compared with various conventional detection methods.

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Pesticide poisoning constantly threatens bees as they forage for resources in pesticide-treated crops. This poisoning requires thorough investigation to identify its causes, underscoring the importance of reliable pesticide detection methods for bee monitoring. Infrared spectroscopy provides reflectance data across hundreds of spectral bands (hyperspectral reflectance), presumably enabling the efficient classification of pesticide contamination in bee carcasses using artificial intelligence (AI) models, such as machine learning.

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The Hodgkin lymphoma International Study for Individual Care (HoLISTIC) Consortium's A-HIPI model, developed in 2022 for advanced-stage classical Hodgkin lymphoma (cHL), predicts survival within 5 years amongst newly diagnosed patients. This study validates its performance in the Brazilian Hodgkin lymphoma registry. By 2022, the Brazilian HL registry included 1357 cHL patients, with a median 5-year follow-up.

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The study of sperm characteristics has proven useful for elucidating interrelationships in several groups of Platyhelminthes, such as digeneans. Thus, in the present work, the ultrastructural organization of the mature spermatozoon of the digenean (Echinostomatidae), a parasite of (Rodentia: Muridae) from Dong Thap Province, Vietnam, was investigated for the first time using transmission electron microscopy. The male gamete of exhibits two axonemes of different lengths, showing the 9 + '1' pattern of the Trepaxonemata, a nucleus, two mitochondria, two lateral expansions, two bundles of parallel cortical microtubules, external ornamentation, spine-like bodies, and granules of glycogen.

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Article Synopsis
  • A phase 2 clinical trial tested the cyclin-dependent kinase inhibitor SCH 727965 in patients with metastatic melanoma to assess its safety and effectiveness, focusing on overall survival and progression-free survival rates.* -
  • Among 72 enrolled patients, there were no observed responses to the treatment out of 67 evaluable cases, with stable disease in only 21%, median progression-free survival at 1.4 months, and median overall survival at 8.2 months.* -
  • Despite some patients achieving a 1-year overall survival rate of 38%, the study concluded that SCH 727965 showed minimal benefit and significant toxic effects, suggesting it should not be further pursued as a single-agent therapy.*
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