Potentiation of Tumor Hallmarks by the Loss of GULO, a Vitamin C Biosynthesis Gene in Humans.

Vitamin C plays a significant role in various physiological functions. Humans depend on external sources of vitamin C due to the loss of the L-gulono-γ-lactone oxidase (GULO) gene that contributes to the synthesis of vitamin C. During the evolutionary loss of the GULO gene, physical, chemical, and biological factors were different from the present environmental settings.

Indian Hand Anthropometry: First Web Space Angle Measurement in A Population of 800 Subjects.

 The first web space of the hand plays a crucial role in determining the hand's span. Our study aims to examine and quantify the first web space angle in both hands of adult individuals within the Indian population with no upper limb pathologies. The primary objective of this study is to establish normative data.

Gait variability and biomechanical distinctions in knee osteoarthritis: Insights from a 3D analysis in an adult elderly cohort.

Background: This study employs 3D gait analysis to investigate normal gait patterns in individuals afflicted with knee Osteoarthritis (OA). Focusing on the adult osteoarthritic population, the research aims to establish reference values for joint angles, temporospatial parameters, Gait Profile Score (GPS), and Movement Analysis Profile (MAP) collected concurrently along a standardized walking path. Furthermore, the study delves into potential variations linked to gender and OA severity, comparing gait parameters between male and female participants and among individuals with grade 3 and grade 4 OA.

Effect of total knee arthroplasty on contralateral knee: A prospective comparative gait analysis of non-operated legs in the Indian population.

Introduction: Biomechanics plays a crucial function in osteoarthritis. Changes in the biomechanical parameters of the contralateral knee following total knee arthroplasty (TKA) may result in pain in the contralateral knee. The objective of this study was to examine preoperative and postoperative gait measurements on the contralateral leg following a TKA for a variety of gait measures at a self-selected normal gait pace in a similar speed population.