Frequency and predictability effects for line-final words.

Computational models of eye movement control during reading have revolutionized the study of visual, perceptual, and linguistic processes underlying reading. However, these models can only simulate and test predictions about the reading of single lines of text. Here we report two studies that examined how input variables for lexical processing (frequency and predictability) in these models influence the processing of line-final words.

Public Health.

Background: The global population of adults over the age of 65 is expected to surpass 2 billion by 2050. Alongside this rise in the aging population, the incidence of age-related cognitive decline and dementia will continue to grow. Importantly, women are at an elevated risk of cognitive decline compared to men.

Public Health.

Background: The Apolipoprotein E (APOE) ε4 variant is the strongest genetic risk factor for Alzheimer's disease (AD) and has been thoroughly studied in non-Hispanic whites (NHW). However, its association with AD among Hispanic individuals is unclear, with existing studies yielding mixed results. Genetics do not entirely explain the likelihood of developing AD.

Biomarkers.

Background: Plasma p-tau biomarkers are promising diagnostic tools for widespread clinical use. However, recent studies have raised concerns regarding the effect of common medical comorbidities, such as cardiovascular disease (CVD), on plasma p-tau specificity. These influences must be better understood to enable appropriate clinical use of p-tau181.

"Gender-Affirming Vaginoplasty Using Robotic Peritoneal Flap Method: Long Term Outcomes of 500 Cases".

Objective: The objective of this study was to determine the outcomes of robotic peritoneal flap vaginoplasty.

Background: There is a lack of long-term outcomes data for gender-affirming vaginoplasty to inform patient decision-making.

Methods: A retrospective cohort of 500 consecutive patients undergoing robotic peritoneal flap vaginoplasty from 2017-2023 were reviewed.