Publications by authors named "A P Maurer"
We report a case of a 33-year-old man with epilepsy and equivocal EEG, MRI signs of mesiotemporal sclerosis, and nondiagnostic standard FDG-PET imaging. The patient underwent repeat FDG-PET/MRI to clarify the sidedness of the epileptogenic focus and to confirm the suspected MTS. The standard PET reconstruction using block sequential regularized expectation maximization failed to provide evidence of a clear epileptogenic focus.
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- This study aimed to explore how different stomach shapes observed in gastric emptying scintigraphy (GES) relate to gastric emptying speeds, body weight, and GI symptoms.
- Researchers reviewed 397 GES studies, identifying five stomach shapes: crescentic, J-shaped, reversed-L, cylindrical, and bag-like, with crescentic being the most common.
- Findings revealed that crescentic stomachs had the highest body mass index (BMI), while bag-like stomachs showed the slowest gastric emptying and more severe regurgitation and heartburn symptoms.
Article Synopsis
- The text discusses the challenge of identifying somatic variants through single-cell RNA sequencing (scRNA-seq) due to issues like low transcript reads and protocol biases, which can miss critical genetic information.
- It introduces SIGURD (SIngle cell level Genotyping Using scRNA Data), an R-based tool designed to analyze scRNA-seq data by combining somatic and mitochondrial variants for more effective clonal analysis.
- SIGURD enables researchers to assess clonal relationships, gene expression changes, and how these variants relate to specific cell populations, as demonstrated through its application on cells from patients with myeloproliferative neoplasms.
Pangenomes are collections of annotated genome sequences of multiple individuals of a species. The structural variants uncovered by these datasets are a major asset to genetic analysis in crop plants. Here we report a pangenome of barley comprising long-read sequence assemblies of 76 wild and domesticated genomes and short-read sequence data of 1,315 genotypes.
View Article and Find Full Text PDFBackground: In the clinical management of advanced stage head and neck squamous cell carcinoma, the use of hybrid [F]FDG-PET imaging is well established. However, there is ongoing debate regarding the optimal frequency of hybrid PET scans to be included in follow-up protocols, particularly if the initial post-therapeutic scan is negative.
Methods: We conducted a single-center 10-year retrospective study involving all patients who underwent hybrid PET scans for the follow-up of advanced stage head and neck cancer.