[Diagnostic and prognostic significance of biochemical indicators in colorectal neoplasms].

Activities of some enzymes and content of medium-weight molecules in patients with colorectal cancer were studied in order to assess the diagnostic value of these parameters for detection of tumors in the large intestine and development of endogenous intoxication after surgery and for prediction of remote results of treatment. Increased activities of creatine phosphokinase and hexokinase is typical of tumor growth, whereas increased activities of alkaline phosphatase and gamma-glutamyl transpeptidase are observed only in metastases to the liver. The role of medium-weight molecules in the diagnosis of endogenous intoxication during the early postoperative period is shown.

[The biogenic amine level of patients with functional and inflammatory diseases of the large intestine].

Patients with functional and inflammatory diseases of large intestine revealed changes of the activity of the sympathetic-adrenal system both in the hormonal and peripheral mediator links, i. e. against the background of pronounced deficit of noradrenaline all groups of patients showed an increased level of adrenalin indicating tension of medullary layer of the adrenal.

[Cyclic nucleotides and serotonin in the blood of patients with functional and inflammatory diseases of the large intestine].

The blood levels of cyclic nucleotides and serotonin were measured in 143 patients with functional and inflammatory diseases of the large intestine. The patients were divided into 3 groups administered various treatment: drug (basic) therapy in Group 1, basic therapy + alternating magnetic field in Group 2, and basic therapy + sinusoidal modulated currents in Group 3. Follow-up of the examined parameters over the course of treatment has shown that by day 16 of inpatient treatment they normalize, this demonstrating the treatment efficacy.