CineECG for visualization of changes in ventricular electrical activity during ischemia.

Background: CineECG offers a visual representation of the location and direction of the average ventricular electrical activity throughout a single cardiac cycle, based on the 12‑lead ECG. Currently, CineECG has not been used to visualize ventricular activation patterns during ischemia.

Purpose: To determine the changes in ventricular activity during acute ischemia with the use of CineECG, and relating this to changes in the ECG.

The CineECG in ischemia localization in ST-elevation (equivalent) acute coronary syndromes.

Aim Of The Study: In this proof of concept study we aimed to visualize and quantify the injury vectors using the CineECG in representative examples of ST elevation acute myocardial infarction (STEMI) and STEMI-equivalent electrocardiograms (ECG's). For this purpose ECG's were selected with different ST deviation patterns in acute anterior wall, inferior or posterolateral wall infarctions.

Methods: The ST-amplitudes of the individual leads were measured between J-point and 60 ms after the J-point.

CineECG illustrating the ventricular activation sequence in progressive AV-junctional conduction block.

We present the use of CineECG in visualizing abnormal ventricular activation in a case of a complex conduction disorder. CineECG combines the standard 12‑lead surface ECG with a 3D anatomical model of the heart. It projects the location and direction of the average ventricular activation and recovery on the heart model over time.

Application of the mineral-binding protein fetuin-A for the detection of calcified lesions.

Calcium plays an essential role in the biology of vertebrates. Calcium content in body fluids is maintained within a narrow physiologic range by feedback control. Phosphate is equally important for metabolism and is likewise controlled, albeit over a wider range.