Immunologic and cytochemical studies were done in 162 patients with myeloid forms of acute leukosis, among whom 130 had acute myeloblastic leukemia (AML), and thirty two--and acute myelomonoblastic leukemia (AMML), before and after the therapy instituted. Immunocorrection was attempted with immunomodulating agents prodigiosane and tactivin. Striking inhibition of T-cellular immunity (T-total, T-active, TPhres, TPhsen, as well as blast transformation of lymphocytes with PHA) was revealed.
View Article and Find Full Text PDFTreatment results were analyzed in 60 patients with acute non-lymphoblastic leucosis. In 30 patients treatment was carried out with consideration of sensitivity of blast cells to chemotherapeutic agents, in 30 polychemotherapy programs were used. Results indicate that individual choice of agents produced a large number of complete clinico-hematological remissions.
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