Publications by authors named "A P Hopper"

We evaluated the antimicrobial performance of sodium hypochlorite (NaOCl) and peracetic acid (PAA) during washing of baby spinach in water of varying levels of organic load, as measured by its chemical oxygen demand (COD). Escherichia coli TVS353 was spot inoculated onto one unwashed leaf. Sanitizers were added into water with preadjusted COD (300 or 2500 ppm) to achieve concentrations from 20 to 80 ppm.

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Eudicot plant species have leaves with two surfaces: the lower abaxial and the upper adaxial surface. Each surface varies in a diversity of components and molecular signals, resulting in potentially different degrees of resistance to pathogens. We tested how Botrytis cinerea, a necrotroph fungal pathogen, interacts with the two different leaf surfaces across 16 crop species and 20 Arabidopsis genotypes.

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Background: Patients with brain tumors demonstrate heterogeneous patterns of cognitive impairment, likely related to multifactorial etiologies and variable tumor-specific factors. Cognitive phenotyping offers a patient-centered approach to parsing heterogeneity by classifying individuals based on patterns of impairment. The aim of this study was to investigate the neuroanatomical patterns associated with each phenotype to gain a better understanding of the mechanisms underlying impairments.

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Article Synopsis
  • Adenoid cystic carcinoma is a challenging cancer that spreads to the lungs and is not effectively treated with systemic chemotherapy, prompting the use of local therapies for management.
  • The case study focuses on a patient who underwent extensive local ablative treatments, including over 850 brachytherapy seeds and stereotactic body radiotherapy (SBRT), to tackle around 80 metastases in the lungs and liver.
  • Remarkably, the patient has survived approximately 12 years post-diagnosis, showcasing the potential success of these localized treatment methods for controlling the disease's progression.
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Background: Patients with primary brain tumors demonstrate heterogeneous patterns of cognitive dysfunction, which we explore using latent profile analysis (LPA) to identify cognitive phenotypes and their trajectories in patients receiving radiotherapy (RT).

Methods: Ninety-six patients completed neuropsychological testing before and post-RT (3, 6, 12-months) on a prospective longitudinal trial, including measures of processing speed, executive function, language, and verbal and visual memory. Models with 2-4 classes were examined.

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