Publications by authors named "A P Garrison"

Introduction: Physicians play a critical role in encouraging their patients to get vaccinated, in part by responding to patients' concerns about vaccines. It is, therefore, important to understand what difficulties physicians have in dealing with different concerns they may encounter. The aim of this article was to determine physicians' perceptions of difficulties in rebutting different antivaccination arguments from patients using data collected as part of a cross-sectional, cross-national questionnaire on physicians' vaccine attitudes and behaviours.

View Article and Find Full Text PDF

Opioid use disorder constitutes a major health and economic burden, but our limited understanding of the underlying neurobiology impedes better interventions. Alteration in the activity and output of dopamine (DA) neurons in the ventral tegmental area (VTA) contributes to drug effects, but the mechanisms underlying these changes remain relatively unexplored. We used translating ribosome affinity purification and RNA sequencing to identify gene expression changes in mouse VTA DA neurons following chronic morphine exposure.

View Article and Find Full Text PDF

Objective: Recent advancements in chest tube technologies have gained interest for their ability to enhance postoperative recovery via reduction of retained blood syndrome after cardiothoracic surgery. The present study investigates the effect of the Centese Thoraguard automated line-clearance chest tube system on postoperative pain and recovery after cardiac surgery.

Methods: This was a single-center retrospective review of 1771 adult patients undergoing nonemergency cardiac surgery between January 2021 and December 2022.

View Article and Find Full Text PDF

Anemia in pregnancy, defined by a hemoglobin level (Hb) of less than 110 g/L, contributes to infant mortality and morbidity in sub-Saharan Africa. Maternal Hb changes physiologically and pathologically during pregnancy. However, the impact of these changes on long-term child neurocognitive function is unknown.

View Article and Find Full Text PDF

Crimean-Congo hemorrhagic fever virus (CCHFV) is a member of the family Nairoviridae in the Hareavirales order and is an important human pathogen. Hepatic injury is a salient feature of CCHF human disease and can be recapitulated in murine models. Here, we described techniques to study liver damage caused by CCHFV in the mouse system.

View Article and Find Full Text PDF