Publications by authors named "A P DeFelipe"
Article Synopsis
- Recent studies suggest a link between COVID-19 and severe acute ischemic strokes, highlighting the need for further research to confirm this association and inform treatment strategies for stroke patients.
- A cohort of 174 COVID-19 patients with acute ischemic stroke was analyzed, revealing that those with COVID-19 generally had more severe strokes compared to non-COVID-19 patients.
- In a matched sample of 336 patients, those with COVID-19 were found to have a higher risk of severe disability and a notable death rate, indicating worse outcomes associated with COVID-19-related strokes.
Background And Purpose: There are no recommendations regarding how to treat cardioembolic recurrent strokes when patients are well anticoagulated. We evaluated the safety and efficacy of combining oral anticoagulation (OAC) with percutaneous left atrial appendage closure (LAAC) in patients with well-anticoagulated atrial fibrillation (AF) with recurrent strokes.
Methods: In an explorative, prospective, observational study, LAAC was performed in patients with AF with at least two ischaemic strokes in the previous year, despite good anticoagulation using the Amplatzer Cardiac Plug (St Jude Medical, St Paul, MN, USA) or Amulet Abbot device (Abbot Vascular, Santa Clara, CA, USA).
Patients with atrial fibrillation and prior stroke or transient ischemic attack exhibit a very high risk of recurrence. Secondary prevention with oral anticoagulants is mandatory. Overall, clinical guidelines recommend the use of target-specific oral anticoagulants over vitamin K antagonists for secondary prevention of stroke in patients with atrial fibrillation.
View Article and Find Full Text PDFThe histiophagous scuticociliate Philasterides dicentrarchi is the aetiological agent of scuticociliatosis, a parasitic disease of farmed turbot. Curcumin, a polyphenol from Curcuma longa (turmeric), is known to have antioxidant and anti-inflammatory properties. We investigated the in vitro effects of curcumin on the growth of P.
View Article and Find Full Text PDFStroke in young adults: Incidence rate, risk factors, treatment and prognosis.
Rev Clin Esp (Barc)
October 2016
Objectives: To analyse the incidence, risk factors, aetiology, treatment and clinical evolution of young patients with stroke.
Patients And Methods: Retrospective registry of patients aged 55 years or younger hospitalised in a stroke unit during 2014. We recorded the incidence rate for all strokes and analysed demographic data, risk factors, degree of stress, stroke type and aetiology, reperfusion treatments and clinical evolution.