Publications by authors named "A P Burgers"
Article Synopsis
- - Huntington's disease (HD) is a genetic disorder that leads to the loss of specific neurons in the brain, causing motor dysfunction, and researchers are exploring cell replacement therapies to restore neuronal function.
- - The study focuses on creating human lateral ganglionic eminence precursors (hiLGEPs) from adult human skin cells through a process called direct reprogramming, which was evaluated for its ability to differentiate into functional neurons.
- - Results showed that hiLGEPs could be successfully produced and transplanted into rats with HD-like symptoms, demonstrating their potential to survive, integrate, and contribute to neuronal function over a 14-week period.
Article Synopsis
- * Research into new atomic species, like alkaline earth atoms, is being explored to enhance coherence and scalability, crucial for quantum error correction techniques.
- * The study introduces a neutral atom qubit based on a long-lived state in Yb, achieving high accuracy in quantum gate operations and effectively managing errors through mid-circuit detection, indicating Yb's potential for fault-tolerant quantum computing.
Neutral atom qubits with Rydberg-mediated interactions are a leading platform for developing large-scale coherent quantum systems. In the majority of experiments to date, the Rydberg states are not trapped by the same potential that confines ground state atoms, resulting in atom loss and constraints on the achievable interaction time. In this Letter, we demonstrate that the Rydberg states of an alkaline earth atom, ytterbium, can be stably trapped by the same red-detuned optical tweezer that also confines the ground state, by leveraging the polarizability of the Yb^{+} ion core.
View Article and Find Full Text PDFReduced volume and reflection for bright optical tweezers with radial Laguerre-Gauss beams.
Proc Natl Acad Sci U S A
October 2020
Spatially structured light has opened a wide range of opportunities for enhanced imaging as well as optical manipulation and particle confinement. Here, we show that phase-coherent illumination with superpositions of radial Laguerre-Gauss (LG) beams provides improved localization for bright optical tweezer traps, with narrowed radial and axial intensity distributions. Further, the Gouy phase shifts for sums of tightly focused radial LG fields can be exploited for phase-contrast strategies at the wavelength scale.
View Article and Find Full Text PDFAt this moment, no method is available to objectively estimate the temperature to which skeletal remains have been exposed during a fire. Estimating this temperature can provide crucial information in a legal investigation. Exposure of bone to heat results in observable and measurable changes, including a change in colour.
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