[Treatment of pathologic hip dislocation caused by hematogenic osteomyelitis in children and adolescents].

The article discusses 94 patients with pathological dislocation of the hip after hematogenous osteomyelitis who underwent reconstructive-restorative operations on 101 joints. According to the clinical and X-ray signs, all patients were divided into 4 main groups. The types of surgical interventions performed depending on the severity of involvement of the proximal part of the femur and the acetabulum are indicated.

[Morphofunctional aspects of genetic analysis of osteogenesis imperfecta in cultured skin fibroblasts].

Osteogenesis imperfecta (OI) is a disease with biochemical evidence of abnormality in collagen biosynthesis. We report here that expression of the OI phenotype extends to the level of dermal fibroblast morphology in vitro. Growth characteristics and morphology of control (n = 3) and 01 cell strains (n = 10) were compared.

[The rehabilitative treatment of children with bone sarcomas].

The paper deals with the experience gained in carrying out rehabilitative surgery in 33 infant patients (37 operations) with bone sarcoma within 12 months to 12 years after combined treatment of primary tumor. Twenty-two operations using procedures of compression-distraction osteosynthesis were performed in 18 patients for post-surgery development of bone deformities and shorter limbs. shortening.

[Current approaches to the development of a system of automated diagnosis of osteochondrodysplasias in children].

On the basis of studying of data on 1469 patients there is proposed a methodology of development of a system of automated diagnosis of osteo-chondrodysplasia in children. It is based on registration of the course peculiarities, variety of clinical and genetic forms, inter- and intragroup similarity and progredient course of diseases of the type. At the first stage there have been made a complex analysis of formalized clinico-roentgenologic signs of osteo-chondrodysplasia with the aid of "Rbase-5000" program package.

[Pathogenetic aspects of studying clonal properties of bone marrow stromal cells in diseases of the osteoarticular system].

Properties of clonogenic stromal fibroblasts of bone marrow which are precursors of osteo- and chondrogenesis, of patients with different diseases of osteoarticular apparatus have been studied. Peculiarities of their reaction on growth-stimulating influence of nonstromal auto- and xenogeneic cells have been demonstrated. The possibilities of data application for studying of pathogenesis of hereditary osteochondrodysplasias as well as other groups of the skeleton affections are considered.