Publications by authors named "A P Accardo"
Background: Ocular following responses (OFRs)-small-amplitude, short-latency reflexive eye movements-have been used to study visual motion processing, with potential diagnostic applications. However, they are difficult to record with commercial, video-based eye trackers, especially in children.
Objective: We aimed to design and develop a noninvasive eye tracker specialized for measuring OFRs, trading off lower temporal resolution and a smaller range for higher spatial resolution.
Article Synopsis
- Peptide building blocks can create supramolecular nanostructures that effectively deliver various drugs while their design impacts the ability of these structures to interact with specific drugs.
- The study focuses on hybrid cationic peptide hydrogels, combining a low-molecular-weight hydrogelator with different cationic amphiphilic peptides to analyze their structural properties.
- Findings indicate that the hydrogel's structure is primarily determined by the hydrogelator, while the peptides' alkyl chain lengths significantly influence the material's morphology, stiffness, and drug encapsulation capabilities.
Article Synopsis
- The study explores how deep learning (DL) can enhance the classification of retinal diseases using OCT images, but faces challenges like variability in conditions and noise in the images.
- The research evaluated the performance of five DL architectures (ResNet18, ResNet34, ResNet50, VGG16, and InceptionV3) on a dataset of 5526 images, focusing on both data scarcity and label accuracy.
- Results showed that with 345 or more training images, DL models can accurately classify retinal pathologies, but labeling errors significantly impair performance, necessitating more training images to offset these errors.
The effect of mechanical cues on cellular behaviour has been reported in multiple studies so far, and a specific aspect of interest is the role of mechanotransductive proteins in neuronal development. Among these, yes-associated protein (YAP) is responsible for multiple functions in neuronal development such as neuronal progenitor cells migration and differentiation while myocardin-related transcription factor A (MRTFA) facilitates neurite outgrowth and axonal pathfinding. Both proteins have indirectly intertwined fates via their signalling pathways.
View Article and Find Full Text PDFNeonatal hyperbilirubinemia (NH) is a common condition in newborns, with elevated bilirubin levels potentially causing neurological damage or death. Accurate and timely measurements of total serum bilirubin are essential to prevent these outcomes. Direct spectrophotometry, a reliable method for measuring bilirubin, is particularly useful in constrained settings due to its potential for portable low-cost instrumentation.
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