Publications by authors named "A Pınar"

Objectives: Both vancomycin (VAN) and teicoplanin (TEI) augment the risk of acute kidney injury (AKI) when combined with piperacillin-tazobactam (TZP). We aimed to compare the risk of AKI among patients receiving TZP-VAN versus TZP-TEI.

Methods: This was a prospective, multinational, multicentre cohort study conducted in 12 centres from Turkiye, Italy and Spain between June 1, 2022, and December 31, 2023.

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Article Synopsis
  • Voriconazole (VCZ) serum concentrations can be influenced by various factors, and this study explores its levels in patients with COVID-19-associated aspergillosis (CAPA) and invasive pulmonary aspergillosis (IPA).
  • The study included 85 patients, finding that about 50.6% had VCZ levels in the therapeutic range, while a significant number had either sub-therapeutic or supra-therapeutic levels, with inflammation markers notably higher in those with supra-therapeutic levels.
  • CAPA patients showed a higher incidence of adverse effects and elevated VCZ levels compared to IPA patients, highlighting the need for more frequent monitoring of VCZ in this group.
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Objectives: To assess both the clinical and immunological effectiveness of diode laser therapy when used as an adjunct to non-surgical mechanical therapy in managing peri-implantitis.

Materials And Methods: A cohort of 27 participants, comprising 21 females and 6 males, agreed to take part in this investigation. 37 dental implants with peri-implantitis diagnosis were randomly allocated to either the laser group (n = 19) or the control group (n = 18).

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There is little evidence of antimicrobial elimination via therapeutic plasma exchange (TPE) and no guidelines for antimicrobial optimal dosing in patients undergoing TPE. We aimed to assess current practices and knowledge regarding antimicrobial management during TPE. A structured online survey was conducted from May to November 2023, and physicians were invited to participate through national scientific platforms and professional societies.

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