Publications by authors named "A Ortiz-Morales"
Article Synopsis
- Atherosclerosis is a major cause of coronary heart disease, and measuring the thickness of the carotid arteries (IMT-CC) helps track its progression, especially in patients with CHD.
- The study aimed to explore the relationship between the total antioxidant content in diets and changes in IMT-CC over 5 years, comparing the effects of Mediterranean and low-fat diet models.
- Results indicated that a higher antioxidant index (DAI) was connected to a decrease in IMT-CC, with specific nutrients like carotenoids, vitamins C and E, and zinc showing significant inverse correlations with IMT-CC changes.
Background: It has been proposed that physical activity (PA) could prevent cognitive decline.
Objective: To evaluate the association between changes in PA and changes in cognitive function in a cohort of adults with metabolic syndrome.
Methods: Longitudinal observational study including 5,500 adults (mean age 65 years, SD = 5; women = 49.
Our work group designed and synthesized a promissory compound N-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA). The HO-AAVPA is a HDAC1 inhibitor and antiproliferative in cancer cell lines. However, HO-AAVPA is poor water solubility and enzymatically metabolized.
View Article and Find Full Text PDFBackground: Mediterranean and low-fat diets are effective in the primary prevention of cardiovascular disease. We did a long-term randomised trial to compare the effects of these two diets in secondary prevention of cardiovascular disease.
Methods: The CORDIOPREV study was a single-centre, randomised clinical trial done at the Reina Sofia University Hospital in Córdoba, Spain.
Background: Inflammation is a common feature in chronic kidney disease (CKD) that appears specifically associated with cardiovascular derangements in CKD patients. Observational studies have revealed a link between low Mg levels and inflammation. In this study, we hypothesize that Mg might have a modulatory effect on the inflammation induced under the uraemic milieu.
View Article and Find Full Text PDF