Publications by authors named "A Ortega-Hernandez"
Microbiota could be of interest in the diagnosis of colorectal and non-small cell lung cancer (CRC and NSCLC). However, how the microbial components of tissues and feces reflect each other remains unknown. In this work, our main objective is to discover the degree of correlation between the composition of the tissue microbiota and that of the feces of patients affected by CRC and NSCLC.
View Article and Find Full Text PDFThe connection between gut microbiota and factors like diet is crucial for maintaining intestinal balance, which in turn impacts the host's overall health. microalgae is a sustainable source of bioactive compounds, mainly known for its used in aquaculture and extraction of bioactive lipids, with potential health benefits whose effects on human gut microbiota are still unknown. Therefore, the goal of this work was to assess the impact of on human gut microbiota composition and derived metabolites by combining the INFOGEST protocol and in vitro colonic fermentation process to evaluate potential effects on human gut microbiota conformation through 16S rRNA gene sequencing and its metabolic functionality.
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- - Alopecia areata (AA) is an autoimmune condition that leads to hair loss, influenced by genetic and environmental factors, with recent studies suggesting that scalp microbiota may affect its progression through inflammatory responses.
- - A study with 24 participants analyzed the scalp microbiomes of those with varying severities of AA and healthy individuals, finding significant differences in microbial communities and their correlation with inflammation and AA severity.
- - Results showed that patients with severe AA had more pro-inflammatory bacteria, while those with milder forms had beneficial bacteria, indicating that scalp microbiota might be linked to AA inflammation, though further research is needed to understand the exact relationship.
The gut microbiota, comprising a diverse community of microorganisms, significantly influences various aspects of health. Changes in the composition of the gut microbiota are implicated in adverse effects on host physiology, contributing to the pathogenesis of cardiovascular diseases, among others pathological conditions. Understanding the role of the gut microbiota in the context of heart failure is particularly important.
View Article and Find Full Text PDFThe application of bacterial metagenomic analysis as a biomarker for cancer detection is emerging. Our aim was to discover gut microbiota signatures with potential utility in the diagnosis of colorectal cancer (CRC) and non-small cell lung cancer (NSCLC). A prospective study was performed on a total of 77 fecal samples from CRC and NSCLC patients and controls.
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