X-ray-Sensitive Doped CaF-Based MRI Contrast Agents for Local Radiation Dose Measurement.

Ionizing radiation has become widely used in medicine, with application in diagnostic techniques, such as computed tomography (CT) and radiation therapy (RT), where X-rays are used to diagnose and treat tumors. The X-rays used in CT and, in particular, in RT can have harmful side effects; hence, an accurate determination of the delivered radiation dose is of utmost importance to minimize any damage to healthy tissues. For this, medical specialists mostly rely on theoretical predictions of the delivered dose or external measurements of the dose.

Formation of carotenoid supramolecular aggregates in nanocarriers monitored aggregation-sensitive chiroptical output of enantiopure (3,3')-astaxanthin.

The aggregation-sensitive chiroptical (ECD and RROA) output, provided by enantiopure (3,3')-astaxanthin, was used to investigate and control the assembling processes of the carotenoid in Pluronic F-127 nanoparticles. The process of carotenoid -aggregation inside nanocarriers is interfered with by the formation of kinetically stabilized self-assemblies outside the micelles. Nanocarriers with encapsulated stable -aggregates provide controlled release of carotenoid molecules to primary murine adipocytes.

Radioactivity induced in new-generation cardiac implantable electronic devices during high-energy X-ray irradiation.

This study provides the first insight into the problem of the induced radioactivity of the construction materials of the new-generation cardiac implantable electronic devices (CIEDs). Its aim was to identify nuclear reactions and the resulting radioisotopes induced in the CIEDs by high-energy X-ray therapeutic beams generated by medical linear accelerators. The presented results allow to verify the rightness of choice of materials for investigated CIEDs.

Influence of a shape of gold nanoparticles on the dose enhancement in the wide range of gold mass concentration for high-energy X-ray beams from a medical linac.

Aim: This work is focused on the Monte Carlo microdosimetric calculations taking into account the influence of the AuNPs' shape, size and mass concentration on the radiation dose enhancement for the high-energy 6 MV and 18 MV X-ray therapeutic beams from a medical linac.

Background: Due to a high atomic number and the photoelectric effect, gold nanoparticles can significantly enhance doses of ionizing radiation. However, this enhancement depends upon several parameters, such as, inter alia, nanoparticles' shape etc.

Application of high field magnetic resonance microimaging in polymer gel dosimetry.

Purpose: The purpose of this work was to examine the suitability of VIPAR polymer gel-9.4 T magnetic resonance microimaging system for high spatial resolution dose distribution measurements.

Methods: The VIPAR samples (3 cm in outside diameter and 12 cm in height) were exposed to ionizing radiation by using a linear accelerator (Varian TrueBeam, USA; 6 MV x-ray beam).