Publications by authors named "A Omri"

This case report describes a rare instance of intraperitoneal rupture in a redegenerated uterine fibroid during pregnancy. A 38-year-old woman at 38 weeks gestation, with a history of a single pregnancy, presented with mild pelvic pain persisting through late pregnancy. An emergency caesarean section was performed due to acute fetal distress during labor.

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  • This study presents the first extensive report on Primary Myelofibrosis (PMF) in Qatar, covering data collected over 13 years, as there is a significant lack of information about PMF in the MENA region.
  • Findings show that pre-PMF patients differ from overt PMF patients in terms of blood counts and genetic features, with overt PMF having a higher risk category and worse disease progression.
  • The research provides important insights into the importance of the DIPSS plus scoring system, highlighting its effectiveness in identifying high-risk patients who face worse outcomes and increased treatment needs.
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  • Dorzolamide hydrochloride (DRZ) is a medication used to lower eye pressure in glaucoma patients, but its effectiveness is limited by a short duration of action and the need for frequent use.
  • Recent advancements in drug delivery systems, such as cyclodextrin complexation and nanotechnology, aim to enhance the bioavailability and effectiveness of DRZ.
  • These innovative systems, including nanoparticle carriers and liposome formulations, provide sustained release and better eye penetration, potentially improving patient compliance and treatment outcomes compared to traditional methods.
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  • * It reviews key barriers within the TME, such as hypoxia and immunosuppression, and explores new approaches like advanced drug formulations and targeting methods.
  • * The article emphasizes the role of emerging technologies, including AI and 3D printing, in improving GBM treatment outcomes by overcoming these biological and structural hurdles.
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Hypoxia is a crucial factor in tumor biology, affecting various solid tumors to different extents. Its influence spans both early and advanced stages of cancer, altering cellular functions and promoting resistance to therapy. Hypoxia reduces the effectiveness of radiotherapy, chemotherapy, and immunotherapy, making it a target for improving therapeutic outcomes.

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