Publications by authors named "A Olkina"

Unlabelled: The individual approach to determining colon resection extension, known as tailored surgery, has been actively discussed for several years. However, despite the consistency and validity of the idea, it still has few followers, primarily due to the lack of high-level evidence confirming the validity of this approach.

Objective: To determine whether the boundaries of the lymphatic outflow area, mapped with indocyanine green, match the lymphogenic metastasis area according to the surgical specimens' pathological study.

View Article and Find Full Text PDF

Background: There is still a lack of randomized trials assessing the clinical value of mechanical bowel preparation (MBP) and oral antibiotics (OA) before rectal surgery. Existing studies are inconsistent regarding OA. The aim of this study is to examine the role of MBP with or without OA (using Alfa Normix) on postoperative complications in patients undergoing rectal resection for cancer.

View Article and Find Full Text PDF
Article Synopsis
  • The incidence of early-onset colorectal cancer (diagnosed in individuals under 50) is on the rise globally, with distinct clinical and molecular characteristics compared to late-onset cases.
  • Factors contributing to this increase may include diet, obesity, antibiotic use, and changes in gut microbiome, with most cases occurring sporadically rather than being genetically inherited.
  • There is a need for tailored preventive and therapeutic approaches for early-onset colorectal cancer, as younger patients often present with more severe disease stages but similar outcomes to older patients after treatment.
View Article and Find Full Text PDF

Background: It remains unclear whether extended lymphadenectomy provides oncological advantages in colorectal cancer. This multicentre RCT aimed to address this issue.

Methods: Patients with resectable primary colonic cancer were enrolled in four hospitals registered in the COLD trial, and randomized to D2 or D3 dissection in a 1 : 1 ratio.

View Article and Find Full Text PDF

Mechanical bowel preparation used to be a standard procedure for a long time. Nowadays routine use of MBP seems to be debatable thus alternative approaches, e.g.

View Article and Find Full Text PDF