Publications by authors named "A Olayinka"
[This corrects the article DOI: 10.1371/journal.pone.
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- Rubella is a major public health issue in developing countries, especially for preventing congenital rubella, and this study focused on children 10 and under in Jos, Nigeria, from May to September 2016.
- Researchers used a multistage sampling method to recruit unvaccinated children from schools, testing for rubella antibodies with the ELISA method and analyzing data using R software.
- Among 405 participants, 82.96% tested positive for rubella IgG, while only 2.22% had IgM, with significant links found between higher seropositivity and factors like being older than 5 years and lacking Western education, indicating a need for a better vaccination program.
Article Synopsis
- * Stool samples from 167 diarrhoea cases and 334 control children were analyzed, revealing DEC strains present in a higher percentage of sick children, especially during the wet season, and linked to factors like caregiver education and breastfeeding practices.
- * The DEC showed high resistance to common antibiotics like sulphonamides and ampicillin, but were mostly susceptible to quinolones and carbapenems, stressing the need for better education and healthcare practices to curb these infections.
Article Synopsis
- Lassa fever, recognized by the WHO as a potential pandemic threat, is a disease with significant health-economic impacts, particularly in West Africa, where it causes millions of infections and disability-adjusted life years (DALYs) each year.
- A study models vaccination strategies and estimates that a preventive campaign targeting endemic regions could save over $20 million in lost DALY value and around $128 million in societal costs over 10 years.
- In the scenario of a new variant, 'Lassa-X', emerging, effective 100 Days Mission vaccination could significantly reduce the potential health burden, illustrating the importance of vaccination in managing Lassa fever and preparing for future pandemics.
Background: Data on the presentation, management, and outcomes of Lassa fever (LF) in children are limited.
Methods: Description of the clinical and biological features, treatment, and outcomes of reverse transcriptase and polymerase chain reaction (RT-PCR)-confirmed LF in children aged under 15, enrolled in the LASsa fever clinical COurse and Prognostic factors in an Epidemic context (LASCOPE) prospective cohort study in Nigeria between April 2018 and February 2023.
Results: One hundred twenty-four children (aged under 12 months: 19; over 12 months: 105) were hospitalized with RT-PCR-confirmed LF.