Kinetic Characterisation of the R and R2 Quaternary Structures of Oxyhemoglobins Arising from Different Effects of Inositol Hexakisphosphate on Their Reactions with Ellman's Reagent.

In a previously reported equilibrium study of the reaction of 5,5'-dithiobis(2-nitrobenzoate), DTNB, with various carbonmonoxyhemoglobins over the pH range 5.6 to 9, we obtained contradictory results on the influence of the allosteric effector inositol hexakisphosphate (inositol-P) on the DTNB reaction. For this reason, we replaced the carbonmonoxyhemoglobins with oxyhemoglobins and investigated the effect of inositol-P on the equilibrium and of their reactions with DTNB over the same pH range.

From Traditional Use to Modern Evidence: The Medicinal Chemistry of Antimalarials from Genus Artemisia.

While the use of plants in traditional medicine dates back to 1500 B.C., modern advancements led to the development of innovative therapeutic techniques.

Durability of bitumen binder reinforced with polymer additives: Towards upgrading Nigerian local bitumen.

One of the major obstacles to Nigeria's techno-economic development has been a lack of good road infrastructure. Despite a large deposit of natural bitumen in the form of semi-liquid and bitumen sand, the reliance on imported bitumen/asphalt for road construction and maintenance in Nigeria has reduced road coverage and quality. To use local bitumen as a binder in pavement construction, an efficient upgrading process is required using polymers, nanomaterials, and other chemical additives.