Cellular function is controlled through intricate networks of signals, which lead to the myriad pathways governing cell fate. Fluorescent biosensors have enabled the study of these signaling pathways in living systems across temporal and spatial scales. Over the years there has been an explosion in the number of fluorescent biosensors, as they have become available for numerous targets, utilized across spectral space, and suited for various imaging techniques.
View Article and Find Full Text PDFRationale: The effect of caffeine mouth rinsing (CAF-MR) on cognitive performance has not been thoroughly investigated.
Objectives: To evaluate the effects of different concentrations of CAF-MR on selective attention in relation to perceived taste intensity.
Methods: A total of 30 healthy and recreationally active male subjects were included in this randomized, double-blind, placebo-controlled crossover trial.
Background: Acute flaccid paralysis (AFP) is a complex clinical syndrome with various aetiologies. If untreated, AFP may lead to death due to failure of respiratory muscles. Tick paralysis, which is a noninfectious neurologic syndrome of AFP, occurs following tick attachment, engorgement, and injection of tick saliva toxins.
View Article and Find Full Text PDFPurpose: To determine older adults' metaphorical perceptions of the concept of aging.
Method: Participants in this qualitative study comprised 57 older adults as determined using convenience and criterion sampling methods. Data were obtained using a personal data form and the metaphor form and analyzed with descriptive and content analysis techniques.