Does Topical Capsaicin Affect the Central Nervous System in Neuropathic Pain? A Narrative Review.

Research has been conducted investigating the neuronal pathways responsible for the generation of chronic neuropathic pain, including the components of it in conditions such as chronic post-surgical pain, phantom limb pain, and cluster headaches. Forming part of the management of such conditions, capsaicin as a molecule has proven effective. This review has investigated the central nervous system modifications exhibited in such conditions and the pharmacological mechanisms of capsaicin relevant to this.

Twin pregnancy involving complete hydatidiform mole and partial mole after five years of amenorrhoea.

A case of twin pregnancy involving a single fetus and complete hydatidiform mole in a 56-year-old woman after 5 years of amenorrhoea is reported. The patient presented with threatened abortion and was managed with bed rest and blood transfusion. Six weeks after admission and at 20 weeks gestation, she had a spontaneous vaginal delivery of a molar pregnancy and a fresh stillbirth with molar degeneration of the placenta.

Primary pyogenic psoas abscess presenting with paraparesis and motor paralytic bladder.

A case of primary pyogenic psoas abscess presenting with paraparesis and motor paralytic bladder is presented. Available literature on primary psoas abscess, the rarity of neurological sequelae and the role of imaging techniques in diagnosis are discussed. A mechanism for the bladder and lower extremity involvement is proffered.

Morphological and biological characteristics of the M-P strain of lymphocytic choriomeningitis virus.

Based on present data, the M-P virus appears antigenically and morphologically to be a strain of the lymphocytic choriomeningitis virus, with some different biological properties.