Publications by authors named "A OE Alpaydin"
Article Synopsis
- Chronic obstructive pulmonary disease (COPD) often leads to hospital readmissions, with a study involving 415 patients in Turkey revealing significant readmission rates of 42.4% within 30 days and 46% within 90 days after severe exacerbations.
- Key risk factors for 30-day readmissions include high anxiety and depression scores, a history of severe exacerbations, hospital-acquired pneumonia, and frequent antibiotic use.
- For 90-day readmissions, factors such as severe heart regurgitation, multiple moderate exacerbations, immunosuppression, and being hospitalized via the emergency department were significant contributors.
Article Synopsis
- COPD exacerbations can lead to increased morbidity and mortality, with prolonged hospital stays linked to various risk factors despite optimal care.
- A study analyzed 434 COPD patients to identify factors influencing hospital length of stay (LOS), categorizing them into patient-related, disease-related, treatment-related, and hospital utility-related.
- Key findings indicated that factors like biomass exposure, previous non-invasive mechanical ventilation, low bicarbonate levels, and increased oxygen needs were associated with difficult-to-manage exacerbations and longer hospitalizations.
Article Synopsis
- Immunoglobulin-G4 (IgG4)-related disease is a rare fibro-inflammatory condition that can impact multiple organs simultaneously or at different times, often presenting with tumor-like organ growth.
- Key affected organs include the lacrimal glands, salivary glands, pancreas, and more, with distinctive histopathological features like dense IgG4-positive plasma cells and storiform fibrosis.
- The disease has an estimated incidence of less than 1 in 100,000 people globally, and a specific case of IgG4-related vasculitis was diagnosed through lung fine needle aspiration biopsy, highlighting its rarity in medical literature.
Article Synopsis
- Latent tuberculosis infection (LTBI) screening is essential for solid organ transplant (SOT) recipients, but many centers in Turkey are not adequately performing these screenings.
- In a study involving 766 SOT patients, 46.9% tested positive for LTBI, but only about half of those treated were registered, and there was a low completion rate of treatment.
- The findings highlight the need for better TB risk assessment and adherence to national guidelines to improve pre-transplant care for SOT recipients in Turkey.
Chronic obstructive pulmonary disease (COPD) that is the third leading cause of death in the world is one of the main economic burden. The cost is primarily due to COPD exacerbations and hospitalizations. We aimed to determine the factors associated with increasing costs in severe COPD exacerbation.
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