Publications by authors named "A O Toure"

Objectives: Assess the effectiveness of ring vaccination in controlling an Ebola virus outbreak in the Democratic Republic of Congo.

Methods: This analysis focuses on two areas of the Democratic Republic of Congo, Beni and Butembo/Katwa, which were affected during the 2018-2020 Ebola outbreak. To simulate Ebola virus transmission, we used a spatially explicit agent-based model with households, health care facilities, and Ebola treatment units.

View Article and Find Full Text PDF

Objective: This study aimed to assess the prevalence and risk factors for neonatal sepsis among neonates admitted to selected health facilities in the Bamako district and Koulikoro region in Mali.

Design: This is a prospective cross-sectional study. Data were analyses using bivariate and multivariate logistic regression.

View Article and Find Full Text PDF

Background: In mammals, sperm fertilization potential relies on efficient progression within the female genital tract to reach and fertilize the oocyte. This fundamental property is supported by the flagellum, an evolutionarily conserved organelle, which contains dynein motor proteins that provide the mechanical force for sperm propulsion and motility. Primary motility of the sperm cells is acquired during their transit through the epididymis and hyperactivated motility is acquired throughout the journey in the female genital tract by a process called capacitation.

View Article and Find Full Text PDF

Background: Several variants of SARS-CoV-2 have a demonstrated impact on public health, including high and increased transmissibility, severity of infection, and immune escape. Therefore, this study aimed to determine the SARS-CoV-2 lineages and better characterize the dynamics of the pandemic during the different waves in Guinea.

Methods: Whole genome sequencing of 363 samples with PCR cycle threshold (Ct) values under thirty was undertaken between May 2020 and May 2023.

View Article and Find Full Text PDF
Article Synopsis
  • Tuberculosis (TB) is a major health issue in Guinea, with many cases going undetected; an intensified case finding strategy involved pharmacies and drug outlets targeting customers buying cough suppressants.
  • A study conducted in Conakry involved screening 916 individuals for TB, resulting in a 14% bacteriologically confirmed TB diagnosis, with gender and age influencing diagnosis likelihood.
  • The intervention cost approximately $32.66 per person referred and $237.45 for those diagnosed, showing that using pharmacies as a TB detection point is both feasible and effective in boosting detection rates.
View Article and Find Full Text PDF