Publications by authors named "A O Oragwa"
Using a metagenomic sequencing approach on stool samples from children with Acute Flaccid Paralysis (AFP), we describe the genetic diversity of Sapoviruses (SaVs) in children in Nigeria. We identified six complete genome sequences and two partial genome sequences. Several SaV genogroups and genotypes were detected, including GII (GII.
View Article and Find Full Text PDFDetection and genetic characterization of orf virus from sheep and goats in Nigeria.
Trop Anim Health Prod
February 2024
Article Synopsis
- The study examines the prevalence and diversity of the orf virus (ORFV), a contagious disease affecting small ruminants, across various regions in Nigeria.
- Out of 54 small ruminants tested, 25 were found positive for ORFV, with the highest rates in Plateau State (50.0%) and the lowest in Oyo State (42.9%).
- The ORFV sequences identified were similar to those found in countries like Taiwan, Iran, USA, and France, highlighting the need for improved surveillance and further studies to understand the virus's transmission and evolution.
Article Synopsis
- - The study highlights the importance of monitoring bats, as they are key reservoirs for coronaviruses (CoVs), particularly in the context of zoonotic diseases like SARS-CoV, which have potential implications for human health.
- - Researchers sampled 409 bats from various species in Nigeria between 2019 and 2021, finding CoV RNA in 39 bats (about 9.5% of samples), with some samples showing co-infection by different CoV lineages.
- - The findings indicate a rich diversity of coronaviruses among bats in Nigeria, suggesting ongoing evolutionary changes and host switching, thus calling for increased surveillance to understand and track emerging CoVs better.
Introduction: Rift Valley fever (RVF) is a zoonotic disease caused by RVF virus (RVFV) and transmitted primarily by mosquitoes and contact with fluids and tissues of infected animals. First described in Kenya, it has spread to many African countries and beyond. In humans, it is sometimes misdiagnosed because the symptoms resemble those of influenza and/or malaria.
View Article and Find Full Text PDFWe recently investigated the presence of enteroviruses (EVs) in non-human primates (NHPs) in Northern Nigeria and documented the presence of EV-A76 of South-East Asian ancestry in an NHP. In this study, we go further to ask if we could also find EVs in NHPs indigenous to the forested South-south Nigeria. Fresh faecal samples were collected from the floor of 10 cages housing NHPs in Cross River Nigeria, re-suspended in PBS and subjected to RNA extraction, cDNA synthesis, PanEnt 5'-UTR and PanEnt VP1 PCR assays.
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