[The cytochemical indicators in patients with II stage hypertension disease and isolated traumas of long tubular bones of lower extremities].

The cytochemical indicators of neutrophils of peripheral blood were analyzed in 30 patients with hypertension disease and isolated traumas of long tubular bones of lower extremities. It is established that in such patients the variations of microbicidal neutrophils systems manifest in the increase of content of cationic proteins and non-significant decrease of myeloperoxidase activity. This is one of mechanisms of immunity support during first 48 hours after trauma.

[Efficiency of anti-inflammatory therapy for experimental tuberculosis in genetically tuberculosis-sensitive mice].

The study assessed trends in death rates in genetically tuberculosis-sensitive I/St mice, mycobacterial seeding from their organs, and the magnitude of abnormal changes in the lung after intratracheal Mycobacterium tuberculosis infection of recipients. The experimental animals received two anti-inflammatory regimens: 1) a very small-dose intravenous injection of immature antigen-loaded bone marrow-derived syngeneic dendritic cells; 2) the nonsteroidal anti-inflammatory drug diclofenac injected intramuscularly in the course of disease development. Both anti-inflammatory regimens caused a significant increase in the animals' survival, a reduction in the amount of mycobacteria in the lung and the pulmonary infiltration with lymphoid cells as compared with untreated infected control animals.

[Comparative assessment of the five-year results of surgical, combined, radiation and chemoradiotherapy in laryngeal cancer (T3N0M0)].

Four modalities of specific treatment for laryngeal cancer were compared in 158 patients. Five-year survival after chemoradiotherapy using cisplatin, 5-FU and bleomycin plus irradiation (65-70 Gy) was 87% versus 69.7; 66.

[Application of the proton pump inhibitors in treatment of an acute gastro-intestinal bleeding of the ulcer etiology].

The results of treatment of 53 patients, suffering an acute gastro-intestinal bleeding of the ulcer etiology are adduced. The proton pump inhibitor Omez infusion have promoted the improvement of the patients treatment results.

[Vilon effect on consequences of repeated radioactive and mercuric impact in small doses].

The purpose of the study was to determine the efficacy of vilon administration in rats after reiterated exposure to ecotoxicants (mercury in concentration near to maximum allowable one and gamma-radiation in small dose). In 24 hours after repeated radioactive and mercuric impact (RMI) and for 30 consecutive days the animals reported lymphopenia. At the same time the indices of DNA leucocytes content and structure did not differ from the parameters of intact animals, this could evidence the development of adaptation reactions.