Publications by authors named "A O Heper"
Grade 4 astrocytoma vs. grade 4 glioblastoma: is there any clue in H&E?
Int J Neurosci
December 2024
Gliomas are the most common primary tumors of the central nervous system. The fifth edition of the World Health Organization (WHO) Classification of Tumors of the CNS identifies IDH mutant astrocytomas grade 4 and IDH wild type glioblastomas grade 4 as distinct entities. This study aimed to identify morphological indicators that could predict IDH mutation status in grade 4 diffuse astrocytomas and grade 4 glioblastomas among fifty patients from two groups.
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- The study analyzed temporal artery biopsy (TAB) results of 90 patients diagnosed with Giant Cell Arteritis (GCA) to determine histopathological findings related to definite vasculitis based on 2022 ACR/EULAR criteria.
- Of the patients, 73.3% were initially diagnosed with vasculitis, and additional evaluation of specimens led to a further 41.6% showing definite vasculitis signs.
- The analysis also revealed that biopsy length was a key indicator for diagnosing definite vasculitis, with a notable sensitivity and specificity ratio, suggesting that longer biopsies improve diagnostic accuracy.
Background: As the majority of T-cell lymphomas lack CD20 expression, cases of mycosis fungoides (MF) exhibiting aberrant CD20 expression are exceedingly uncommon.
Objectives: To comprehensively evaluate the clinical, histopathological and prognostic features of seven patients diagnosed with CD20+ MF.
Methods: This retrospective study involved seven cases of MF with aberrant CD20 expression.
Linear basal cell carcinoma (BCC) is a distinct clinical morphological variant of BCC. Although it has been speculated that trauma and the Koebner phenomenon may be linked to linear BCC, the pathophysiology has not yet been shown. Herein, 5 cases of BCC were presented that developed in the postauricular region as a result of trauma caused by the cords of the medical face masks worn during the COVID-19 pandemic.
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