Publications by authors named "A O Direev"

Unlabelled: In an aging society, age-dependent diseases with high mortality, including cardiovascular diseases (CVD) and type 2 diabetes mellitus (DM2), occupy a special place. There is only limited population-based data on the relationship between cardiometabolic diseases and target-organ damage, including ocular microvasculature.

Purpose: To explore the associations between the caliber of retinal vessels and cardiometabolic diseases in a population sample of men and women from middle-aged to elderly (Novosibirsk).

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. To study the associations of risk factors for chronic non-communicable diseases (CNCDs) and osteoporotic fractures (OFs) in a population sampling over 50 years. .

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The changes of retinal vascular caliber and microvascular topography reflect the cumulative response to ageing, the influence of cardiovascular risk factors, inflammation, endothelial dysfunction. With objective to perform a systematic review of the studies which evaluate retinal vessels in ageing, we conducted the search of published reports (2003-2020). The review provided the evidence of narrowing of the caliber of retinal arterioles and venules in ageing; inverse relationship has been found in ethnically heterogeneous populations in a wide age range from 4th to 9th decade.

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Unlabelled: The ageing of population is accompanied by an increase in the frequency of chronic diseases, including ophthalmic. The progression of ophthalmologic disturbances has population specificity and its analysis in Russian population is relevant.

Purpose: To study the prevalence and age- and gender-related gradient of ophthalmic diseases (cataract, glaucoma, age-related macular degeneration, diabetic and hypertensive retinopathy) in the Russian population older than 50 years.

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