Introduction: Introduction: Rheumatic heart disease (RHD) is a major public health issue, especially in developing countries. Globally, the largest increase in RHD incidence over 30 years was seen in sub-Saharan Africa, further contributing to the burden of cardiovascular disease in a region with high rates of hypertensive heart disease and cardiomyopathies. There are few reports describing the contemporary clinical profile of RHD in Nigeria.
View Article and Find Full Text PDFBackground: Human immunodeficiency virus (HIV) is a lentivirus. It is transmitted through sexual intercourse, shared intravenous drugs, contaminated needle use, blood transfusion, and mother-to-child transmission. Of the patients with HIV, 50%-75% have ocular manifestations and this may be the primary presentation.
View Article and Find Full Text PDFExtraction of organic and bioactive compounds from plant materials with the traditional organic solvents aided by water or oil bath heating is not sustainable, because it consumes a lot of energy, time, water/oil, solvents, and results in lower yield. This review discusses deep eutectic solvent (DES) as a green solvent, physical field technology (PFT) as a water-saving and green technology, and how the coupling of PFT (ultrasound [US], microwave [MW], infrared [IR]) to DES will improve the yield and quality of protein, polysaccharides, polyphenols, pectin, and terpenoids extracted from plant materials. Ultrasonication increases DES extraction efficiency via cavitation dislodgement and pores creation.
View Article and Find Full Text PDFThe parasitic weed Striga (Striga hermonthica) limits productivity of sorghum (Sorghum bicolor) and other cereals in sub-Saharan Africa and elsewhere. Improved host plant genetics is an effective control method but verified loci contributing to Striga resistance are limited. LOW GERMINATION STIMULANT 1 remains the only known sorghum locus affecting resistance to Striga.
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