The rise of antimicrobial resistance is a global public health crisis that threatens the effective control and prevention of infections. Due to the emergence of pandrug-resistant bacteria, most antibiotics have lost their efficacy. Bacteriophages or their components are known to target bacterial cell walls, cell membranes, and lipopolysaccharides (LPS) and hydrolyze them.
View Article and Find Full Text PDFFruits and vegetables are sources of parasitic infections in humans. This study was designed to determine the epidemiology of parasitic contamination of fruits, vegetables, and water, as well as the perception of retailers, buyers, and consumers about its contamination in Kwara Central, Nigeria. A cross-sectional study design was employed for this study.
View Article and Find Full Text PDFAims: Neurodegenerative disorders like Alzheimer's disease (AD) are outcomes of neuroinflammatory processes that result in memory impairment. Quercetin (QT), a plant based flavonoid, has demonstrated notable effects against neurodegeneration and inflammation in models of dementia. However, the underlying mechanisms have not been well elucidated.
View Article and Find Full Text PDFDespite the promising neuroprotective activities of quercetin (QT), its' effect on cholinergic neurotransmission needs further elucidation. In this study, we explored the impact of QT on oxidative stress and cholinergic neurotransmission with emphasis on the possible involvement of choline acetyltransferase (ChAT) as a potential mechanism of QT on memory function at the hippocampal sub-regions and prefrontal cortex of mice brains. Mice were administered orally with QT (12.
View Article and Find Full Text PDFIntroduction: The aim of this article is to summarize published information on systemic infective complications of tattoos to gain an update of the current picture.
Methods: A literature search was performed in PubMed database (2009-2019), and compared with a search without year restriction. Eligibility criteria were studies on systemic tattoo-related infections, including case reports, case series, outbreak investigations, reviews, and systematic reviews.