Publications by authors named "A Nowinski"

Background: Since the Russian Federation's invasion of Ukraine, millions of refugees have moved to neighbouring European countries. We assessed the burden of TB in these refugees and surveyed screening approaches.

Methods: We conducted a survey among 30 European Union/European Economic Area and 13 other European countries, requesting population data on migrant residents and refugees with country of birth (COB) Ukraine, the number of TB notifications among people with COB Ukraine and countries' screening policies for refugees from Ukraine.

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Article Synopsis
  • International guidelines emphasize the importance of airway clearance management in treating bronchiectasis, yet its actual usage across Europe remains unclear.
  • A study involving 16,723 patients from 28 countries showed that 52% reported using regular airway clearance, with significant variation in techniques and usage between countries.
  • Patients using airway clearance tended to have more severe disease and symptoms, and access to specialized respiratory physiotherapy was notably low, especially in Eastern Europe.
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Article Synopsis
  • - The study utilized a 4-point sputum colour chart to assess airway inflammation in bronchiectasis patients, analyzing data from 13,484 individuals across 31 countries in the EMBARC registry.
  • - Findings revealed that more purulent sputum correlates with worse lung function, a higher severity of the disease, increased frequency of exacerbations, and greater risk of hospitalizations and mortality.
  • - The research concluded that sputum colour serves as an effective, straightforward indicator for predicting clinical outcomes and disease severity in bronchiectasis patients.
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Background: Asthma is commonly reported in patients with a diagnosis of bronchiectasis.

Objective: The aim of this study was to evaluate whether patients with bronchiectasis and asthma (BE+A) had a different clinical phenotype and different outcomes compared with patients with bronchiectasis without concomitant asthma.

Methods: A prospective observational pan-European registry (European Multicentre Bronchiectasis Audit and Research Collaboration) enrolled patients across 28 countries.

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Background: Deoxycholic acid (DCA) is a secondary bile acid produced by gut bacteria. Elevated serum concentrations of DCA are observed in cardiovascular disease (CVD). We hypothesized that DCA might influence hemodynamic parameters in rats.

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