Posterior tibial somatosensory evoked potentials a comparative study of responses elicited by transcutaneous and percutaneous stimulation at the popliteal fossa.

Nine healthy volunteers underwent posterior tibial nerve stimulation at the popliteal fossa with recordings of averaged potentials being taken from the lumbar spine and cortex. Stimulation was attempted in all subjects both transcutaneously and percutaneously. A comparison of the responses to the two stimulating methods was made.

Influence of a 'brain protector' drug 21-amino steroid on the effects of experimental embolic stroke treated by thrombolysis.

This study was designed to evaluate the effects of tissue-type plasminogen activator (tPA) and 21- amino steroid (U74006F) in experimental embolic stroke in rabbits. The size of infarction from embolism was compared to controls with tPA alone, 21-amino steroid alone, and in combination. The middle cerebral artery of the rabbit was embolized by injecting an arterial ('white') thrombus in the right internal carotid artery.