Publications by authors named "A Niwinska"
Article Synopsis
- The unconventional yeast species is a rich source of protein and nutrients, particularly kynurenic acid (KYNA), which may positively influence metabolism as shown in a nutritional experiment with mice.
- The study compared high-KYNA and low-KYNA yeast by analyzing KYNA content, amino acid composition, and antioxidant indicators using high-performance liquid chromatography.
- Results indicated that while high-KYNA yeast had a greater KYNA concentration, it had lower crude protein and less favorable amino acid composition, but did not significantly impact body weight or food intake in mice, though some trends in blood parameters were observed.
Neoadjuvant Pertuzumab Plus Trastuzumab in Combination with Docetaxel and Carboplatin in Patients with HER2-Positive Breast Cancer: Real-World Data from the National Institute of Oncology in Poland.
Cancers (Basel)
February 2022
Neoadjuvant systemic therapy has now become the standard in early breast cancer management. Chemotherapy in combination with trastuzumab +/- pertuzumab targeted therapy can improve the rates of pathologic complete response (pCR) in patients with HER2-positive breast cancer. Achieving a pCR is considered a good prognostic factor, in particular, in patients with more aggressive breast cancer subtypes such as TNBC or HER2-positive cancers.
View Article and Find Full Text PDFBackground: Determining the proper therapy is challenging in breast cancer (BC) patients with brain metastases (BM) due to the variability of an individual's prognosis and the variety of treatment options available. Several prognostic tools for BC patients with BM have been proposed. Our review summarizes the current knowledge on this topic.
View Article and Find Full Text PDFDetailed and direct analysis of semen, including sperm morphology, enables a diagnosis of male fertility. This study aimed to describe an economical and verified protocol for canine spermiograms and compare the effectiveness of Sperm Stain and Sperm Blue (Microptic, Spain) in veterinary practice. Sperm assessment was conducted manually, using a standard optical microscope, and via computerized semen analysis using the SCA CASA (Sperm Class Analyzer CASA System-MICROPTIC, Spain).
View Article and Find Full Text PDFBrain metastases are detected in 5% of patients with breast cancer at diagnosis. The rate of brain metastases is higher in HER2-positive and triple-negative breast cancer patients (TNBC). In patients with metastatic breast cancer, the risk of brain metastases is much higher, with up to 50% of the patients having two aggressive biological breast cancer subtypes.
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