Choosing optimal first-line Helicobacter pylori therapy: a view from a region with high rates of antibiotic resistance.

Helicobacter pylori is a gram-negative, microaerophilic spiral bacillus that is associated with life-threatening diseases such as gastric cancer, gastric MALT lymphoma, and peptic ulcer disease. The definition of an effective therapy is one that achieves at least a 90% eradication rate on a per-protocol basis with the first attempt. Eradication rates of H.

Nifuratel-containing initial anti-Helicobacter pylori triple therapy in children.

Background: Proton pump inhibitor-containing triple therapy with amoxicillin and metronidazole is recommended as initial treatment of Helicobacter pylori in childhood. However, eradication rate with this "classic" regimen is relatively low in Russia.

Aim: To evaluate empiric nifuratel, amoxicillin, and bismuth triple therapy for H.

Helicobacter pylori eradication in childhood after failure of initial treatment: advantage of quadruple therapy with nifuratel to furazolidone.

Background: Failures of Helicobacter pylori eradication in children are common.

Aim: To evaluate the efficacy of amoxicillin, bismuth subcitrate and omeprazole and nifuratel or furazolidone for H. pylori eradication in children who failed initial treatment with a standard triple therapy.

Helicobacter pylori and gastrointestinal symptoms in school children in Russia.

Background And Aims: Helicobacter pylori is considered to be the major cause of chronic gastritis and duodenal ulcer disease recurrence in childhood. However, the association between H. pylori and recurrent abdominal pain (RAP) syndrome is still controversial.

Helicobacter pylori infection and reflux esophagitis in children with chronic asthma.

Background: Reflux esophagitis is uncommon in countries in which most people are colonized by H. pylori infection and is extremely rare in persons with reflux esophagitis, although esophagitis is detected in almost 50% of children with recurrent lower respiratory tract symptoms.

Hypothesis: Failure to acquire H.