Publications by authors named "A Nieto Soria"
The global incidence of metastatic melanoma with BRAF mutations, characterized by aggressive behavior and poor prognosis, is rising. Recent treatment advances, including immune checkpoint inhibitors (ICI) and targeted therapies (TT) such as BRAF and MEK inhibitors, have significantly enhanced patient outcomes. Although guidelines recommend sequencing strategies, real-world implementation can be influenced by clinical scenarios.
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- Coleus forskohlii supplements (FKSs), popular for weight management due to forskolin, face issues like fraud and adulteration.
- A new method using Flow Injection Analysis-Mass Spectrometry (FIA-MS) was developed to effectively detect these issues in FKSs.
- The method revealed that 45% of tested samples did not contain forskolin, and there was a 69% discrepancy between the actual and labeled forskolin content, demonstrating FIA-MS as a reliable technique for quality assessment.
Objectives: This study aims to provide model-based cost-utility estimates for the addition of inspiratory muscle training (IMT) in COVID-19 pulmonary rehabilitation (PR).
Methods: A cohort model comparing IMT with PR (intervention group) to IMT with only PR (control group) was used. The payer perspective from the Unified Health System in Brazil was adopted.
Background: Regulatory T (Treg) cells are pivotal in immune tolerance to allergens. Low-dose IL-2 (IL-2) activates Treg cells.
Objective: Our aim was to assess IL-2 efficacy for controlling clinical responses to allergen exposures.
Background: Immune checkpoint inhibitors (ICI) have changed the therapeutic landscape of many solid tumors. Modulation of the intestinal microbiota by antibiotics (Abx) has been suggested to impact on ICI outcomes.
Methods: Retrospective analysis of 475 patients with advanced solid tumors treated with ICI from 2015 to 2022.