Relationship between vaginal and gut microbiome and pregnancy outcomes in eastern Ethiopia: a protocol for a longitudinal maternal-infant cohort study (the EthiOMICS study).

Introduction: Although evidence exists on the impact of microbiota on pregnancy outcomes in many high-resource settings, there is a lack of research in many low-resource settings like Ethiopia. This study aims to fill this gap by studying the gut and vaginal microbiota changes throughout pregnancy and assess how these changes relate to pregnancy outcomes among a cohort of pregnant women in eastern Ethiopia.

Methods And Analysis: Vaginal and stool samples will be collected using DNA/RNA Shield Collection kits three times starting at 12-22 weeks, 28-36 weeks and at birth (within 7 days).

Molecular and clinical insights into extended-spectrum β-lactamase genes of Klebsiella pneumoniae isolated from neonatal sepsis in Ethiopia.

Background: Klebsiella bacterial strains harboring Extended-Spectrum Beta-Lactamase (ESBL) enzymes are the primary culprits behind neonatal sepsis globally. These strains significantly impact clinical outcomes due to their multi-drug resistance patterns in local healthcare settings. In response to this spiraling threat, we studied the prevalence and clinical implications of ESBL-encoding genes in neonates hospitalized with confirmed sepsis.

Further analysis of determinants of Pentavalent and Measles immunizations dropouts among children under five years of age in Ethiopia from Mini-EDHS 2019.

Background: Globally, immunization prevents an estimated 2-3 million deaths from illnesses that can be prevented by vaccination. The predictors of Pentavalent and Measles immunization dropout were not investigated sufficiently. Therefore, this analysis was meant to determine the coverage, burden, and predictors of Pentavalent and Measles immunizations in Ethiopia.

Labor Pain Management in Ethiopia: A Systematic Review and Meta-Analysis.

Objectives: Labor pain is a subjective phenomenon that varies based on women's expectations. To have a positive childbirth experience, laboring women should have pain relief based on their request. Therefore, this study aimed to determine the utilization of labor pain management and associated factors among obstetric caregivers in Ethiopia DATA SOURCES: Different electronic databases (i.

The complications of traditional uvulectomy and concurrent occurrences of cultural malpractices in Ethiopia: A systematic review and meta-analysis.

Introduction: Despite the establishment of a national strategy and plan to eliminate all harmful traditional practices, traditional uvulectomy remains widely practiced in Ethiopia, and there is a lack of comprehensive summary of national data on uvulectomy complications and associated malpractices. Therefore, this study aimed to assess the pooled complications of uvulectomy and concurrent occurrences of traditional malpractices in Ethiopia.

Methods: The following databases were used to retrieve studies: PubMed, EMBASE, CINAHL, Google Scholar, Web of Science, MEDLINE, Cochrane Library, SCOPUS, and Google Search.