Publications by authors named "A Nayir"

Background: To assess depression, anxiety, and other psychological disorders in adolescents with chronic kidney disease (CKD) and determine the significant factors and the effect of digital media use on its scores among these patient groups.

Methods: The study was conducted as a cross-sectional study and included 84 adolescents with CKD and 68 healthy controls. The participants completed the Revised Child Anxiety and Depression Scale (RCADS).

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Introduction: In the pediatric context, most children with autosomal dominant polycystic kidney disease (ADPKD) maintain a normal glomerular filtration rate (GFR) despite underlying structural kidney damage, highlighting the critical need for early intervention and predictive markers. Due to the inverse relationship between kidney volume and kidney function, risk assessments have been presented on the basis of kidney volume. The aim of this study was to use magnetic resonance imaging (MRI)-based kidney volume assessment for risk stratification in pediatric ADPKD and to investigate clinical and genetic differences among risk groups.

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Background: Compared with the general population, the immune response to COVID-19 mRNA vaccines is lower in adult kidney transplant recipients (KTRs). However, data is limited for pediatric KTRs. In this study, we aimed to assess humoral and cellular immune responses to the COVID-19 mRNA vaccine in pediatric KTRs.

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Article Synopsis
  • A new study looked at a special urine test called uHSP70 to help tell if kids have a urinary tract infection (UTI) instead of just using regular tests that might not be very reliable.
  • The study involved 802 kids and found that uHSP70 levels were much higher in kids with UTI compared to those with other infections or who were healthy.
  • Using uHSP70 could help doctors correctly diagnose UTIs and might stop about 80% of kids from getting unnecessary antibiotics.
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Article Synopsis
  • The study analyzed 25 genetically confirmed cases of PLCε1-related kidney disease to explore the clinical spectrum, genotype-phenotype correlations, and treatment impacts on kidney outcomes.
  • 36% of patients presented with isolated proteinuria, while others had nephrotic syndrome or chronic kidney disease, with significant variations in histopathology results among those biopsied.
  • The findings suggest that while genetic variations do not correlate with clinical presentations, the type of kidney condition and histological features significantly influence prognosis and treatment responses.
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