Publications by authors named "A Nayar"
Ultra long-range genomic contacts, which emerge as prominent components of genome architecture, constitute a biochemical paradox. This is because regulatory DNA elements make selective and stable contacts with DNA sequences located megabases away, instead of interacting with proximal sequences occupied by the same exact transcription factors (TF). This is exemplified in olfactory sensory neurons (OSNs), where only a fraction of Lhx2/Ebf1/Ldb1-bound sites interact with each other, converging into highly selective multi-chromosomal enhancer hubs.
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- The study aimed to explore the effectiveness of McConnell's sign in predicting normotensive shock in patients with intermediate-risk pulmonary embolism (PE).
- Researchers analyzed patients who received percutaneous mechanical thrombectomy and defined normotensive shock based on specific blood pressure and cardiac output metrics.
- Results showed that McConnell's sign was associated with higher instances of normotensive shock and other indicators of poor outcomes, suggesting it could be a valuable predictive tool, though further research is needed to confirm these findings.
In this study, we found that a low LVOT VTI (<15 cm), a simple bedside point-of-care measurement, predicts normotensive shock in patients with acute intermediate-risk PE.
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- Mechanical complications after an acute myocardial infarction are rare but can greatly increase the risk of severe health issues and death, necessitating thorough clinical assessment.
- This review covers the symptoms, diagnostic approaches, and treatment options for these complications, with a highlight on the use of echocardiography as a key diagnostic tool.
- Recent advances in percutaneous structural interventions offer non-surgical treatment options, and understanding various echocardiographic techniques is crucial for effectively managing these complications and improving patient outcomes.