Impact of a Pharmacist-Driven Poststroke Transitions of Care Clinic on 30 and 90-Day Hospital Readmission Rates.

Background: Stroke impacts nearly 800,000 people annually and the risk of recurrent stroke and hospital readmission is increased early following the initial event. Due to the increase in morbidity and mortality associated with secondary events, a pharmacist-driven poststroke transitions of care clinic was created at Methodist University Hospital to provide risk factor modification in an effort to decrease risk of recurrence and hospital readmissions.

Methods: A retrospective matched-cohort study was conducted between 9/1/2017 and 2/28/2019.

Phospholipid and cholesterol differences amongst leukemic cell types with special reference to hairy cell leukemia: a preliminary report.

Whole cell cholesterol and phospholipid content was determined for ten patients with hairy cell leukemia (HCL) and 15 patients with chronic lymphocytic leukemia (CLL). Malignant cells from HCL patients contained 0.412 mumol/10(8) whole cells is compared to 0.

Comparison between the cellular proteins of hairy cell leukemia and the leukemic phase of other lymphoproliferative diseases.

Cellular proteins from malignant cells of the leukemic phase of hairy cell leukemia and other lymphoproliferative diseases characterized by immunological markers were evaluated by sodium dodecyl sulfate gradient-polyacrylamide gel electrophoresis. The protein patterns from eight patients with hairy cell leukemia were essentially identical. The protein patterns from eight patients with chronic lymphocytic leukemia, seven patients with acute lymphocytic leukemia, and four patients with poorly differentiated lymphocytic lymphoma were examined and did not demonstrate a consistent pattern within each disease.

Preparation and characterization of plasma membrane-enriched fractions from rat pancreatic islets.

Methods have been developed for the isolation on a semi-micro scale of a plasma membrane-enriched fraction from rat islets of Langerhans. An important feature of these experiments is the use of 125I-labeled wheat germ agglutinin as a specific probe for plasma membrane-containing fractions. The partly purified plasma membrane fraction had a density in sucrose of about 1.

Biosynthesis of insulin and glucagon: a view of the current state of the art.

It is now well established that insulin biosynthesis proceeds through a precursor molecule, proinsulin. This single polypeptide chain form has been identified as a ribosomal product in the microsomal fraction from islet tissues. The newly synthesized peptide chain, after folding and thiol oxidation, is transferred to the Golgi apparatus where it begins to undergo proteolytic processing to insulin and packaging into secretory granules.